Lymphadenopathy and hepatosplenomegaly in a patient with acute myelogenous leukaemia

Lymphadenopathy and hepatosplenomegaly in a patient with acute myelogenous leukaemia.

1 of 2 DESCRIPTION An 18-year-old man was admitted to our hospital with fever and generalised lymphadenopathy in October 2010. One month prior to admission, a submaxillary nodule appeared, with gradually progression to nodes involving the entire body. His medical history was unremarkable, and he was not receiving any medication. Physiological parameters were: body temperature, 37.7°C; heart rat...

Ovarian sarcoma and acute myelogenous leukaemia.

VP 16-213 in acute myelogenous leukaemia.

The use of the epipodophyllotoxin VP 16-213 is described in twenty patients with acute myelogenous leukaemia resistant to other chemotherapy. The drug was usually given in 5-day courses of 50 mg/M2 daily and occasionally in 24-hr infusions of 250 mg/M2, on the basis of its phase-activity. Complete remission was achieved in only two patients: in one of these, remission was maintained with VP 16-...

Acute Transformation In Chronic Myelogenous Leukaemia

Fifty-three patients with chronic myeloid leukaemia (CML) were included in this study (25 females & 28 males) and followed-up from October 2003 till October 2005 included for the evidence of acute transformation. Twenty-one patients (39.6%) transformed to acute phase , 16 patients(76.1%) of them transformed during the first 4 years of diagnosis. Fifteen patients (71.4 %) ) transformed to acute ...

Acute myelogenous leukaemia in Hurler's syndrome.

The occurrence of the Hurler syndrome and acute myelogenous leukaemia in a 2 1/2-year-old girl is described. This represents the first published report of the concurrence of these two diseases.